Noninvasive imaging technologies generate information which is of fundamental importance for understanding the normal and dysfunctional human brain and invaluable for a better treatment of neurological and psychiatric disorders. However, the full benefit from these studies can only be attained in the context of a comprehensive understanding of the brains structural/functional organisation. Today, this information is largely fragmented, excessively parochial and often contradictory. The proposed conference will bring together leading minds in contemporary neuroscience to establish a solid foundation for a credible consensus on the structural/functional organization of the normal and abnormal human brain. The conference participants will co-operate in deriving a state-of-the-art knowledge base of the normal human brain. This will set the stage for the emergence of concepts regarding the functional interaction of brain structures and structural alterations associated with diseases of the brain. The reciprocal benefits of fundamental neuroscience and clinical neurology and rehabilitation will be addressed.